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Ole Miss vs. Florida: Final odds and predictions

Pankti Parmar
Pankti Parmar

Ole Hotty Toddy

Nov 8, 2025; Oxford, Mississippi, USA; Mississippi Rebels head coach Lane Kiffin walks the sideline during the fourth quarter against The Citadel Bulldogs at Vaught-Hemingway Stadium. Mandatory Credit: Petre Thomas-Imagn Images / Petre Thomas-Imagn Images

It's officially Lane Kiffin Bowl day.

The No. 6 Ole Miss Rebels welcome what would be one of their most-anticipated opponents of the season, the Florida Gators.

The Vaught-Hemingway will soon turn into a madhouse this Saturday with Ole Miss and Florida fans packed in one place.

All the rumors having Lane Kiffin as Florida's next head coach increase the cinematic factor of this showdown tenfold.

It will also be the perfect day for both fan bases, and frankly, the whole of college football, to catch some direct response from Kiffin about the Florida rumors.

Besides the drama, a win against the Gators would also warrant a first-round home game in the college football playoff bracket after the committee dropped them a spot in the previous week's rankings.

Since Florida is an unranked opponent, even a dominant win against them won't significantly bump up the Rebels' rankings, but it will make sure they don't drop below where they are.

Here are what the odds say about the game.

Ole Miss vs. Florida odds

Ole Miss enters the gameday as the clear favorite to win the game. Meanwhile, Florida will strive to continue their winning streak in the series history and pull another wild upset over the Rebels, despite being the heavy underdogs.

Spread: Ole Miss -14.5 (-110), Florida +14.5 (-110)

Over/Under: 53.5, Ole Miss over -115 , Florida under -105

Moneyline: Ole Miss -671, Florida +490

Odds are courtesy of FanDuel Sports book as of Saturday, Nov. 15.

Ole Miss vs. Florida predictions

Whether Billy Gonzales gives DJ Lagwway a chance vs. Ole Miss will make all the difference here. The Rebels defense has made ample of improvements to score atleast a couple of interceptions from Lagway, if he plays today.

If so, the game will tip largely in favor of Ole Miss. If not, Tramell Jones is still largely a mystery, but not as much of a threat for Pete Golding's defense to hold off.

Then, of course, Kewan Lacy will continue his streak of massive scores once again, putting up big numbers against Florida as well.

Besides the offense, the QB room is now even more productive with both Trinidad Chambliss and Austin Simmons available.

Whoever plays will make a formidable score for the Gators to match, overpowering them with atleast three or more touchdowns, and a two-score game.

Ole Miss vs. Florida picks

Ole Miss: 45, Florida: 28

Pankti Parmar

Pankti Parmar

Pankti is currently the site expert at Ole Hotty Toddy. With over 3 years of expeirnce covering college sports, she has previously served as a contributor at Glory Colorado and Fly War Eagles, alongside her exprience at the Sporting News, Pro Football & Sports Network and more. She completed her Bachelor's in Psychology in 2024 from St. Xavier's.