The Ole Miss Rebels finally return home after two grueling weeks against Georgia and Oklahoma, which also saw the Rebels get their first loss of this season.
They welcome the South Carolina Gamecocks this Saturday as their next SEC opponent they face at home. The 7-1 Rebels are coming off a comeback win against the best-in-the-nation defense in Oklahoma.
Whereas the 3-5 Gamecocks are coming off an almost upset over Alabama last Saturday, making it clear that they could still pull an upset over a major SEC heavyweight such as Ole Miss.
It will be an interesting late kickoff between the two SEC teams as Ole Miss prepares for their almost sure college football playoff appearance.
How to Watch South Carolina vs. Ole Miss
- Date: Saturday, November 1, 2025
- Time: 7:00 p.m. ET
- Venue: Vaught-Hemingway Stadium, Oxford, Miss.
- How to watch (TV): ESPN
- Streaming: ESPN
- Radio: Ole Miss Radio Network
- Ole Miss Rebels record: 7-1
- South Carolina Gamecocks record: 3-5
Ole Miss vs. South Carolina odds
The Ole Miss Rebels are heavy odds on favorites entering the Week 10 matchup.
Spread: Ole Miss -12.5 (-114) South Carolina +12.5 (-106)
Moneyline: Ole Miss -549, South Carolina +410
Total (Over/Under): 55.5 (-110)
Odds are courtesy of FanDuel Sportsbook as of 31 Oct.
Who are the announcers for Ole Miss vs. South Carolina?
With ESPN broadcasting the game, the network's crew will be at the Vaught-Hemingway Stadium calling the game. Bob Wischusen (play-by-play) and Louis Riddick (analyst) will be on the call, while Kris Budden will be reporting from the sideline.
Weather report
It will be another classic late kickoff in Oxford on Saturday. With the fall settling in, temperatures are expected to drop into the 40s by kickoff, accompanied by some brisk chills in the Grove.
Ole Miss vs South Carolina Series history
The Rebels and the Gamecocks have a rather shorter history of facing off against each other. Ever since the two first played in 1947 till they last met in 2024, Ole Miss has been leading their head-to-head record by a margin of two wins at 10-8.
Two of those 10 wins against South Carolina came in their last two matchups, the only two matchups they have faced against Kiffin's Ole Miss.
That is one of the reasons why Kiffin's team is highly favored to pull this one off against the Gamecocks and further cement their case for the college football playoffs.